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It belongs to a new generation of incretin-based compounds often called triple agonists because of their ability to simultaneously activate three distinct metabolic receptors: the glucose-dependent insulinotropic polypeptide receptor (GIPR), the glucagon-like peptide-1 receptor (GLP-1R), and the glucagon receptor (GCGR)
Large-scale clinical trials are necessary to confirm the therapeutic effects of glutathione
Novel insights into the protective effects of leonurine against acute kidney injury: inhibition of ER stress-associated ferroptosis via regulating ATF4/CHOP/ACSL4 pathway
The non-DAC version is commonly evaluated in research settings where shorter-duration pathway activity and time-sensitive signaling analysis are relevant to the experimental design
In patients with AS and depression, elevated levels of the inflammatory factors IL-6 and IL-10 are observed (Mousa et al., 2022), while ferroptosis exerts a significant pro-inflammatory effect
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